HITMAN: Patient Zero Requiem — Silent Assassin, Suit Only Walkthrough

The Patient Zero Requiem campaign brings one of the most thrilling and highly anticipated Elusive Targets to Hitman World of Assassination: Lilith Devereux. Played by Hollywood star Milla Jovovich, Devereux is the cold, calculated incoming CEO of the Ether Biotech Corporation. Backed by her powerful political ally and romantic partner, Gregory Carlisle, her rapid ascent to power hides a dark, biological threat.

Taking down this formidable duo while securing the coveted Silent Assassin, Suit Only (SASO) rating is the ultimate test of a player's stealth capabilities. Bypassing heavy security at Thornbridge Manor in Dartmoor without ever changing out of Agent 47’s signature suit requires precise timing, environmental awareness, and deep knowledge of NPC pathing.

This professional guide breaks down the flawless SASO route, explaining not just what to do, but why these strategic choices are critical to maintaining your perfect rating.

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Mission Breakdown: Step-by-Step Strategy

Phase 1: Infiltration and Reconnaissance

• Blending In at the Fundraiser [0:00:00]: The mission begins with Agent 47 entering the grand hall of the Carlisle Estate under an alias. At this stage, you are perfectly safe in your default suit, as you are attending a public fundraiser. Use this brief window to orient yourself and prepare for the sequence of events.
• Observing the Speech [0:00:07]: Lilith Devereux takes the stage to outline her vision for Ether’s future. Standing in the crowd allows you to observe her and Gregory's dialogue without drawing suspicion.
• The Strategic Catalyst [0:00:55]: Gregory Carlisle presents a traditional ring to Lilith. This moment is crucial—it signals the end of their public presentation and sets their subsequent movement patterns into motion.
• Triggering the Target Movement [0:01:31]: Agent 47 approaches Gregory and Lilith for a brief interaction. In Hitman, understanding NPC triggers is the key to routing. Initiating this conversation is what prompts the targets to leave the crowded ground floor and head upstairs to their private quarters, where they can be safely isolated.

Phase 2: Scaling the Manor

• Tailing the Targets [0:02:35]: As the targets begin to ascend to the upper levels of the mansion, 47 follows closely. Keeping a visual lock on them is necessary to ensure they proceed without unexpected delays, but you must keep your distance to avoid raising guard suspicion.
• Bypassing Security via the Ledges [0:03:03]: To maintain the "Suit Only" restriction, you cannot simply walk through the heavily guarded upper corridors, as guards will immediately spot you as a trespasser. The solution? Slip outside and navigate the mansion's exterior window ledges. This allows you to bypass every single checkpoint and slip directly into the targets' private quarters completely unseen.

Phase 3: Silent Execution

• Neutralizing Gregory Carlisle [0:03:31]: Once inside the private quarters, 47 moves into the bathroom to isolate Gregory. With Gregory separated from his guards and Lilith, he is swiftly and silently subdued.
• Securing the Scene [0:03:43]: Immediately after subduing Gregory, his body is hidden inside the wardrobe. Leaving a body out in the open, even in a locked room, is an unnecessary risk that can instantly strip away your Silent Assassin rating if a patrolling guard wanders in.
• Confronting the Primary Target [0:04:15]: With Gregory neutralized, 47 steps into the bedroom to confront Lilith Devereux. Because her protector is gone, she is completely vulnerable.
• Target Eliminated [0:04:34]: Lilith is cleanly eliminated. By keeping the execution swift and quiet, no alarms are raised, and the rest of the manor remains entirely unaware of the assassination.

Phase 4: The Clean Escape

• Exfiltrating the Estate [0:04:47]: With both targets dealt with and their bodies hidden, 47 retraces his steps back down the exterior of the mansion, avoiding the remaining guards on the ground floor. He slipstreams to a motorcycle parked on the estate grounds for a quick escape.
• Mission Accomplished [0:05:07]: The screen confirms a flawless run: the contract is complete, and the pristine Silent Assassin, Suit Only rating is secured.

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Key Tactical Takeaways

• The Power of Dialogue Triggers: Many players make the mistake of waiting for targets to move on their own loop. By actively engaging Gregory and Lilith at [0:01:31], you force them into a predictable, isolated pathing sequence, saving valuable time.
• Alternative Navigation is King: When going for "Suit Only", the environment is your best friend. The window ledges at [0:03:03] are the single most important routing choice of the run, rendering the mansion's tight interior security completely useless.
• Isolate and Conquer: Taking out Gregory Carlisle first at [0:03:31] ensures that Lilith has no backup when you enter the bedroom, turning what could be a messy double-assassination into a controlled, clean sweep.